Endocrine Abstracts

Introduction: The diagnosis of Cushing’s syndrome (CS) can be challenging for endocrinologists due to its multifaceted presentation. Accurate differentiation between Pseudo-Cushing syndrome (PCS) and true CS is crucial as their treatment approaches and outcomes vary significantly.Case Report: A 43-year-old male patient with grade III obesity (BMI: 49.9 kg/m2) presented to our Endocrinology outpatient clinic with a complex medical history ...

Background: It has been reported that some Magnetic Resonance Imaging (MRI) pituitary findings may reflect specific endocrinological alterations, as in the case of adult-onset growth hormone deficiency (GHD), which has already been associated with lower MRI-derived pituitary height and volume in pediatric patients.Purpose: The objective of this study was to investigate potential associations between pituitary morphology and signal intensity on MRI with G...

Background: Oxytocin (OXT) enhances glucose uptake and lipid utilization in adipose tissue and skeletal muscle.Dysfunction of the OXT system could underlie the pathogenesis of weight gain. Men and women with obesity were reported to have higher OXT blood levels compared to normal weight subjects. In contrast, metabolic syndrome has been associated with reduced fasting serum oxytocin in larger scale mixed gender studies.Aim: Data regarding the oxytocin sy...

Introduction: Adult growth hormone (GH) deficiency has been associated with the onset of sarcopenic obesity, reduced bone mineral density, and the progression of metabolic syndrome, often accompanied by the accumulation of ectopic fat at the epicardial level and changes in echocardiographic measures.Objective and Design: This prospective pilot study aimed to assess the impact of recombinant human GH (rhGH) replacement therapy on glyco-metabolic parameter...